※ MiCroKiTS Protein Information


Tag Content
Uniprot Accession P53_HUMAN; P04637; Q15086; Q15087; Q15088; Q16535; Q16807; Q16808; Q16809; Q16810; Q16811; Q16848; Q2XN98; Q3LRW1; Q3LRW2; Q3LRW3; Q3LRW4; Q3LRW5; Q86UG1; Q8J016; Q99659; Q9BTM4; Q9HAQ8; Q9NP68; Q9NPJ2; Q9NZD0; Q9UBI2; Q9UQ61
MiCroKit ID MCK-HS-00033
Entrez ID 7157
Genbank Protein ID NP_000537.3; NP_001119584.1; NP_001119585.1; NP_001119586.1; NP_001119587.1; NP_001119588.1; NP_001119589.1; NP_001119590.1; NP_001263624.1; NP_001263625.1; NP_001263626.1; NP_001263627.1; NP_001263628.1; NP_001263689.1; NP_001263690.1
Genbank Nucleotide ID NM_000546.5; NM_001126112.2; NM_001126113.2; NM_001126114.2; NM_001126115.1; NM_001126116.1; NM_001126117.1; NM_001126118.1; NM_001276695.1; NM_001276696.1; NM_001276697.1; NM_001276698.1; NM_001276699.1; NM_001276760.1; NM_001276761.1
Protein Name Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
Gene Name TP53; P53
Organism Homo sapiens (Human); NCBI Taxa ID= 9606
Localization
Localization PMID (Show Figures) Orthologs
Centrosome 15181149; 15806166; 15865924; 7513706 (View/Close)
Functional Description Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the (View all)
PTM
Count: 24
(View all)
PositionPeptideDescriptionSource
9 EEPQSDPSVEPPLSQPhosphoserine; by HIPK4 UniProt
15 PSVEPPLSQETFSDLPhosphoserine; by CDK5, PRPK, AMPK, NUAK1 and ATM UniProt
18 EPPLSQETFSDLWKLPhosphothreonine; by CK1, VRK1 and VRK2 UniProt
20 PLSQETFSDLWKLLPPhosphoserine; by CHEK2, CK1 and PLK3 UniProt
33 LPENNVLSPLPSQAMPhosphoserine; by CDK5 and CDK7 UniProt
37 NVLSPLPSQAMDDLMPhosphoserine; by MAPKAPK5 UniProt
46 AMDDLMLSPDDIEQWPhosphoserine; by CDK5, DYRK2, HIPK2 and PKC/PRKCG UniProt
55 DDIEQWFTEDPGPDEPhosphothreonine; by TAF1 and GRK5 UniProt
120 FLHSGTAKSVTCTYSN6-acetyllysine; by KAT6A UniProt
183 CPHHERCSDSDGLAPPhosphoserine; by AURKB UniProt
269 GNLLGRNSFEVRVCAPhosphoserine; by AURKB UniProt
284 CPGRDRRTEEENLRKPhosphothreonine; by AURKB UniProt
305 ELPPGSTKRALPNNTN6-acetyllysine UniProt
315 LPNNTSSSPQPKKKPPhosphoserine; by AURKA, CDK1 and CDK2 UniProt
370 RAHSSHLKSKKGQSTN6,N6-dimethyllysine; alternate UniProt
370 RAHSSHLKSKKGQSTN6-methyllysine; by SMYD2; alternate UniProt
372 HSSHLKSKKGQSTSRN6-methyllysine; by SETD7 UniProt
373 SSHLKSKKGQSTSRHN6,N6-dimethyllysine; by EHMT1 and EHMT2; alternate UniProt
373 SSHLKSKKGQSTSRHN6-acetyllysine; alternate UniProt
381 GQSTSRHKKLMFKTEN6-acetyllysine UniProt
382 QSTSRHKKLMFKTEGN6,N6-dimethyllysine; alternate UniProt
382 QSTSRHKKLMFKTEGN6-acetyllysine; by KAT6A; alternate UniProt
382 QSTSRHKKLMFKTEGN6-methyllysine; by SETD8; alternate UniProt
392 FKTEGPDSD******Phosphoserine; by CK2, CDK2 and NUAK1 UniProt
Sequence
(Fasta)
MEEPQSDPSV EPPLSQETFS DLWKLLPENN VLSPLPSQAM DDLMLSPDDI EQWFTEDPGP DEAPRMPEAA PPVAPAPAAP 80
TPAAPAPAPS WPLSSSVPSQ KTYQGSYGFR LGFLHSGTAK SVTCTYSPAL NKMFCQLAKT CPVQLWVDST PPPGTRVRAM 160
AIYKQSQHMT EVVRRCPHHE RCSDSDGLAP PQHLIRVEGN LRVEYLDDRN TFRHSVVVPY EPPEVGSDCT TIHYNYMCNS 240
SCMGGMNRRP ILTIITLEDS SGNLLGRNSF EVRVCACPGR DRRTEEENLR KKGEPHHELP PGSTKRALPN NTSSSPQPKK 320
KPLDGEYFTL QIRGRERFEM FRELNEALEL KDAQAGKEPG GSRAHSSHLK SKKGQSTSRH KKLMFKTEGP DSD 393